Clinically Backed: How Active Guard Helps Reduce Inflammation Naturally

When it comes to gut health, it's not just about what you eat, it’s also about how your body reacts during the healing process. That’s why we’re proud to share that Active Guard isn’t just supported by personal stories, it’s backed by clinical science.

🧪 The Study Behind Active Guard

Researchers from Okayama University and Sonoda Women’s University in Japan set out to explore how fermented plant extracts (FPE), the core ingredient in OSN Active Guard—impact inflammation and gut health.

Three groups of mice were studied:

1. Control group: Fed a normal diet.
2. Inflammation group: Given a diet that causes inflammation.
3. Active Guard group: Given the same inflammatory diet plus FPE.

The Results? Striking.

• Mice in the inflammation group experienced shorter, darker intestines with signs of internal bleeding. Inflammation markers  TNF-α and IL-6 spiked.
• Meanwhile, the Active Guard group showed pinker, longer intestines. TNF-α and IL-6 levels stayed low.
• Conclusion? Active Guard helped reduce visible gut damage and controlled inflammation markers.

👩🔬 What About Humans?

In a follow-up 3-month study with healthy women:

While the mouse study showed clear anti-inflammatory effects of Active Guard’s fermented plant extract (FPE), the researchers didn’t stop there—they also tested how it affects real people.

👩 Who Was Involved?

• 20 healthy young women aged 20–24.
• Divided into two groups: one group took FPE daily for 3 months, the other took a placebo.

 🍓What Did They Take?

Participants in the FPE group took 1 sachet of fermented plant extract (same formula as Active Guard) three times a day after meals, with no other changes to their diet or lifestyle.

 📏What Was Measured?

Before and after the 3-month period:

• Stool samples were collected.
• Gut bacteria were analyzed using 16S rRNA sequencing.
• Physical health metrics like body weight, body fat, and muscle mass were also tracked.

🧠 What Changed?

No major differences were found in body weight or health condition between the FPE and placebo groups. But what changed significantly was gut bacteria.

The group taking FPE showed:

• A significant increase in Firmicutes, a phylum of bacteria known to support digestion and overall gut health.
• A marked increase in the Clostridiales order, especially families like Lachnospiraceae and Ruminococcaceae.

✅ Why this matters:

These bacteria are butyrate producers. Butyrate is a short-chain fatty acid that:

• Reduces gut inflammation
  
• Strengthens the gut lining
  
• Encourages growth of anti-inflammatory regulatory T-cells
  
• Helps the immune system tolerate good bacteria while fighting off harmful ones

In contrast, the placebo group showed no meaningful changes in microbiota.

Modern medicine often focuses on suppressing symptoms quickly. But natural healing takes time and works from the inside out. Active Guard doesn’t just mask problems—it supports your gut’s journey back to balance.

🏆 Conclusion:

OSN Active Guard helps reduce inflammation, supports your gut lining, and promotes healthier gut bacteria. Backed by science, not just claims.

Because a healthy gut is where true healing begins.

Clinical report here